Click that 'hood is a web-based, open-source game that quizzes your knowledge of a city's neighborhoods. Hover over the neighborhood to learn the names as you're being timed on an easy quiz (keep going until you get them all correct)! There are many US cities and a bunch of European ones, too.
I just tried San Francisco and it took me 2:44 minutes to get it all correct!
Geography nut? Want to learn there neighborhoods before traveling to that city? Have fun!